Some Thoughts on Michaeld Pollan's Newest Book & Clones

By Steve Campbell

In his newest book, In Defense of Food, Michael Pollan writes:

The first time I heard the advice to "just eat food" was in a speech by the nutritionist and author Joan Gussow, and it baffled me. Of course you should eat food - what else is there to eat? But Gussow, who grows much of her own food on a flood-prone finger of land jutting into the Hudson River, refuses to dignify most of the products for sale in the supermarket with that title. "In the 34 years I've been in the field of nutrition," she said, "I have watched real food disappear from large areas of the supermarket and from much of the rest of the eating world." Taking its place has been an unending stream of food-like substitutes - "products constructed largely around commerce and hope, supported by frighteningly little actual knowledge."

Real food is still out there, still being grown and even occasionally sold in the supermarket. I agree with Michael's advice to help you recognize it, and then make the most of it.

Don't eat anything that your great-grandmother wouldn't recognize as food.

Why your great-grandmother? Because at this point your mother, and possibly even your grandmother, are as confused as the rest of us. To be safe we need to go back at least a couple generations, to a time before the advent of most modern foods. Some nutritionists recommend going back even further. John Yudkin, a British nutritionist whose early alarms about the dangers of refined carbohydrates were overlooked in the 1960s and 1970s, once advised: "Just don't eat anything your Neolithic ancestors wouldn't have recognised and you'll be OK."

Is Cloned Meat Safe?

More than 100 nuclear transfer procedures could be required to produce one viable clone. In addition to low success rates, cloned animals tend to have more compromised immune function and higher rates of infection, tumor growth, and other disorders. Japanese studies have shown that cloned mice live in poor health and die early.

About a third of the cloned calves born alive have died young, and many of them were abnormally large. Many cloned animals have not lived long enough to generate good data about how clones age. Appearing healthy at a young age is not a good indicator of long-term survival. Clones have been known to die mysteriously. For example, Australia's first cloned sheep appeared healthy and energetic on the day she died, and the results from her autopsy failed to determine a cause of death.

In 2002, researchers at the Whitehead Institute for Biomedical Research in Cambridge, Massachusetts, reported that the genomes of cloned mice are compromised. In analyzing more than 10,000 liver and placenta cells of cloned mice, they discovered that about 4% of genes function abnormally. The abnormalities do not arise from mutations in the genes but from changes in the normal activation or expression of certain genes.

Problems also may result from programming errors in the genetic material from a donor cell. When an embryo is created from the union of a sperm and an egg, the embryo receives copies of most genes from both parents. A process called "imprinting" chemically marks the DNA from the mother and father so that only one copy of a gene (either the maternal or paternal gene) is turned on. Defects in the genetic imprint of DNA from a single donor cell may lead to some of the developmental abnormalities of cloned embryos.

In sum, this is just not a good idea.

Steve Campbell